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In the four-month pilot trial, Sethi’s team followed 21 adult participants who were diagnosed with schizophrenia or bipolar disorder, taking antipsychotic medications, and had a metabolic abnormality — such as weight gain, insulin resistance, hypertriglyceridemia, dyslipidemia or impaired glucose tolerance. The part...

Losing weight is, for most people, the easy part. The bigger challenge is trying to keep it off for more than a year.New research helps explain why people in this second stage are so much more prone to failure.In a nutshell, people who have shed a significant chunk of their weight are hungrier and have a stronger de...